Projects Proposed 2003 - Fall
(See also archive materials for 2002 and 2001, some of these projects
remain...) Projects marked with a
strikethrough have been
taken. If you are interested in them, you may wish to see if the current
team needs a new member...
|contact information/project description|
|1. Dr. Bill Walsh, email@example.com (also Dan Lindstrom) (Neonatology)|
|1. Program a face recognition computer to recognize
syndromes with abnormal faces (using commercially available software.)
2. We have new ventilators which keep track of each breath the infant takes I would like to report to other neonatologists the number of times an hour a baby fights against the ventilator by downloading data from the ventilator. The project would be to download and analyze data from a neonatal ventilator.
3. ... also there was a student last year looking at organizing all the wires and cords but that project was not completed to my knowledge.
4. I have a design in mind for new new type of medical instrument to facilitate chest tube insertion the project would be to create and test and compare the new instrument versus the existing instrument in an animal model. We have the animal available for chest tube insertion already and use the model to teach house staff, it would be easy to get an addendum to test the new device. Might be too simple for your students.
5. The "Holy Grail" project would still be to determine the resting lung volume of a neonate non-invasively. Figuring out the residual volume in a container in vitro would be the first step.
|2. Mark Richter, MSME, Research Engineer, Beneficial Designs, 3301 Cobble Street, Nashville TN 37209, 837.6902 x2, firstname.lastname@example.org|
|1) Wheelchair Propulsion Simulator (WPS):
There is a high incidence of upper extremity overuse injuries among the
manual wheelchair user population. Researchers have found the magnitude and
rate of loading on the upper extremity during propulsion to be associated
with incidence of injury. There are several variables which can be studied
in an effort to reduce demands on the upper extremity during propulsion.
Current research in this field is limited to studies involving human subject
testing. While the ultimate goal is to improve the human/machine interface,
the variability found in human subject testing can make discerning small
outcomes difficult if not impossible. Use of a repeatable Wheelchair
Propulsion Simulator (WPS) would allow researchers to study the effects of
small design changes on the wheelchair users. Results from the WPS will be
validated using a human subject study. Beneficial Designs (Nashville) is
equipped with a wheelchair propulsion biomechanics laboratory, machine
tools, CAD facilities, data acquisition equipment, and a variety of sensors.
Students will have access to the Beneficial Designs resources.
3. Thomas J. Limbird M.D.,Associate Professor, Department of Orthopedic Surgery, thomas.j.limbird@Vanderbilt.Edu
Fractures that occur just above total knee prostheses (para-prosthetic fractures) are particularly difficult to treat due to the relatively little bone one has to work with. One of the current methods is to run an intramedullary nail up through the knee prosthesis and fix the nail to the femur with screws. It would be nice if we could somehow attach the prosthesis to the nail as well and create a much more rigid construct that would maintain the desired alignment. I would like to design an adaptor that would connect the nail and the prosthesis. I’ve got a knee, I can get a nail, and then I need someone with ideas. If you think this would be suitable for your students, let me know; otherwise I will look to the nail manufacturers for advice.
|4. Dr. Tom Cleveland, Otolaryngology, Tom.Cleveland@vanderbilt.edu|
1. At the
conclusion of every voice box exam with a rigid telescope, we have to clean
the scope. This process includes leaving the scope in
Cidex for 20 minutes which requires the tending of the
cidex containers as the
cidex can damage the scope seals if left in the solution too long. Is
it possible that an engineer might create a device that would deliver
cidex to a container upon command, leave the
cidex in the container for the required 20
minutes, and then empty to cidex into a storage
container for subsequent use. That way, the integrity of the scope seals
would not be jeopardized by remaining in the fluid too long.
|5. Rich Fries, Datex-Ohmeda Corp., email@example.com|
|6. Stephen Bruehl, Ph.D., Assistant Professor of Anesthesiology, 504 Oxford House, 936-1821, stephen.bruehl@Vanderbilt.Edu|
|My research is in the area of pain. As part of this research, we use a standardized acute pain stimulus to compare responses under placebo and under blockade of various receptors. What I need is a copy of, or an improvement on, a finger pressure stimulator we have used before. It is basically a small open-topped metal box with adjustments in 3 axes (i.e., vertically and horizontally) to keep the subject's index finger centered and at the proper height under a fulcrum which applies pressure to the upper surface of the index finger using a rounded Lucite tip that will not break the skin. We have used approximately 4-5 pounds of pressure in the past, but ideally the weight would be adjustable as would the height of the table it is mounted to. Also ideally, we would have a pressure transducer that would allow us to accurately judge the amount of weight being applied to the finger. I have a version of this that I am not totally satisfied with because the weight is not adjustable, there is no functioning pressure transducer, and it looks haphazard (I had to modify it on my own with Home Depot materials because the original engineering company made it incorrectly). This version could at least be used as a basis for the student to get an idea of what I would like. Please contact me by e-mail or by phone if you are interested.|
|7. Chuck Matthews, M.S. Ph.D., Center for Health Services Research, firstname.lastname@example.org , .936.2145|
|See section 8 (below) and 23...|
|8. Robert V. Allen, MicroNova Technology, email@example.com|
Per our discussion, I am pleased to forward what MNT perceives as its current intellectual property for each of the design projects previously submitted. In each case, we would like to have Vanderbilt acknowledge that the current intellectual property listed below belongs to MNT and any improvements generated through the projects would be shared equally between Vanderbilt and MNT.
Also, as in the past, we
need the following from each student working on our projects.
Project 1 – Development of a Leadless Surface Mount Micro-Sized Load Cell
This project is among the very highest of future revenues and proprietary rights for MNT and at least for the next few months cannot be a part of the design projects due to disclosure restrictions. MNT owns the Micro-LID™ Leadless Surface Mount packaging technology (dry-pressed ceramic and metallization techniques) as purchased from Alberox / Frenchtown Ceramics on August 18, 1993. MNT owns the load cell application concepts of this device and is currently in the process of completing a provisional patent. This provisional patent is expected to be filed by our patent and IP attorneys, Myers Bigel Sibley Sajovec (MBSS,) shortly after a scheduled meeting on October 10, 2003 in Nashville. Once this provisional patent is filed, the project may move forward in all haste with MNT owning the patent rights and application concepts and any improvements to assembly processes and test data generated owned equally and mutually publishable by Vanderbilt and MNT.
Project 2 – Design and Development of a Lightweight and Portable “Walker – Lifter”
To the best of our knowledge, no students have selected this project. All rights to intellectual property for this project (including patents) may be shared equally between Vanderbilt and Robert V. Allen / Judith A. Allen. The primary objective of this project is to develop a potentially patentable and reasonable cost orthopedic walker for commercial applications.
Project 3 – Design of an ASIC from a Forced Electrical Stimulator Micro-Flex Design
MNT owns the original schematic design. All development and improvements of the “ASIC-able” part of this schematic may be shared equally between Vanderbilt and MNT. The full schematic design of the working Micro-Flex assembly is immediately available and it is anticipated that partitioning to isolate the portion of the schematic that will comprise the ASIC device through design, fabrication, and test will follow a natural flow consistent with classroom instruction and project milestones, with performance results to represent a “best efforts” basis as close as practical to the original performance of the Micro-Flex assembly. MNT’s primary objective of this project is to learn how to specify ASIC biomedical implantable devices for volume-oriented human and/or animal applications. Project assumed under EE/CS direction.
Project 4 – FDA Approval Qualification of a Micro-Flex Hybrid Design
All rights to intellectual property for this project may be equally shared between Vanderbilt and MNT and the results are highly encouraged to be published in a professional forum. Most of the equipment is available at MNT’s facilities and Vanderbilt’s equipment contributions to complete the project would be major failure analysis items such as SEM, SAM, FIB, and possibly autoclave. At this time, MNT is searching the used market for an autoclave and at one time MNT understood that Vanderbilt may have had a surplus autoclave in storage. MNT needs about four (4) weeks to procure parts and assemble samples to test and the test will need to include a 1000 hour (six week) operating life test at elevated temperature with weekly interim readings at 168, 336, 504, 672, and 840 hours. Investigation of non-lead solders assembled on polyimide flex circuitry and performance of parylene or related coatings should also be a part of the project.
Please call me or Ben at our new 914 Building number, 662-3104, or my private number 662-0023 if you have any questions or comments. I would suspect that we should be able to formalize a document related to MNT versus Vanderbilt intellectual property for student design projects fairly rapidly. Also, Ben’s and my email are respectively firstname.lastname@example.org and email@example.com.
|9. Dr. Raul Guzman, firstname.lastname@example.org Vascular Surgery|
|10. Dr. Ted Larson, email@example.com|
|Investigate methodologies to assist in the centering of microcatheters in the bloodstream.|
|11. Doyle, Thomas [thomas.doyle@Vanderbilt.Edu] Cardiology|
|12. Dr. Paul King|
|1. Prototype and test an emergency ventilator
3. Develop a concept map scoring system for use in assessment tasks.
|13. Dr. David Black, Aegis|
|1. Continue/complete project 1 from last year|
14. Marshall Summar, M.D., Associate Professor of Pediatrics and Molecular Physiology & Biophysics, 322-7601
|1. We had an interesting idea for looking at clinical measures of oxidative phosphorylation capacity involving muscle stimulators and isoprostanes. It might make a very good student project this year.|
|15. Anita Mahadevan-Jansen Ph.D. 343 4787|
|16. Dr. Frank Carroll, frank.carroll@Vanderbilt.Edu ., # 3-7574|
|1. Design of a special purpose
scanning mammography table for use with monochromatic x-rays.
2. Image analysis improvements, improved image reconstruction algorithms.
4. Cancer treatment and some related research which need some technical assistance.
(Note, these projects will likely require multidisciplinary teams!)
|17. Dr. Cynthia Paschal|
|Variations in local magnetic fields lead to distortions and signal loss in a very fast type of magnetic resonance images called echo planar images. Drs. Fitzpatrick, Yoder, Paschal and colleagues have developed a method to correct for these distortions. A Master of Engineering level project supervised by Dr. Paschal would be to develop a precise and reproducible device to place into the MR scanner a small object that will intentionally distort the local magnetic field, to investigate materials of different magnetic susceptibilities to be used as the distorting object, to measure the susceptibility of the object and device combined, and to develop measures of quantifying the effect of the distorted field on the images.|
|18. Dr. Mark Wathen mark.wathen@Vanderbilt.Edu|
|Implanted Cardiovertor Defibrillators (ICD) must first detect tachycardias then treat them as they occur in real time in an automated fashion. This means that detection of arrhythmias is first based on heart rate. However, the devices really want to treat only Ventricular Tachycardias (VT) (arising from the ventricles) and not Supraventricular Tachycardias (SVT)(which arise from the atria). The former are life threatening and the latter not. The treatment delivered by the ICD is a shock: A LARGE and uncomfortable shock. Thus the device to be developed needs to distinguish VT from SVT... (See King for more details)|
|19. Scott Levin, MS candidate ( Scott.R.Levin@Vanderbilt.edu ) and Dan France, PhD|
|20. Monique Bird, firstname.lastname@example.org speech/language pathologist, Bill Wilkerson Center 936-5212|
|I am currently working with a twelve year, four-month old girl, named Jenny, who has Cerebral Palsy. She is seated in a wheelchair, mom reported that Jenny received new padding for the back of her chair in order provide the appropriate support for Jenny. Jenny also has a Dynavox 3100, a voice output communication device which is mounted to her wheelchair on the left side. Jenny accesses the device through direct selection using the knuckles of her left fisted hand. This continues to be the most effective and preferred mode of selection. However, Jenny's movements are not under her control, and often her physical movements interfere with her performance. Since the installation of the new padding, mom had felt that the device was too far for Jenny to access. Mom had indicated that she moved the mount closer to Jenny, however, it took over 2 hours for her to do this. Now with the device moved closer to Jenny, I am still finding that Jenny has some difficulty accessing symbols that are to the far left of the screen and on the bottom of the screen. I am not sure if it is the way the device is placed on the mount or if the mount needs to be moved on the wheelchair.|
|21. Michael I. Miga [email@example.com] 343-8336|
|22. Russ Waitman [firstname.lastname@example.org] (Medical Informatics)|
|If you had a group with good programmers and an interest in clinical data, I have some interesting projects. Specifically, I am working on developing a tool to let clinican's review orders by unit as well as by patient's with the goals of helping manage staffing (operational) and looking for patient specific events (odd ordering in the middle of the night leading to a code possibly) with a goal on patient safety|
|23. Chuck Matthews, M.S. Ph.D., Center for Health Services Research, email@example.com 936.2145|
Handheld Physical Activity Diary/Record:
The measurement of
free-living physical activity levels, to estimate physical activity energy
expenditure or to describe the amount of time spent in different
types/intensities and activity, is methodologically challenging because
physical activity is done intermittently throughout the day, occurs in many
different social domains (e.g., at home, work, for recreation), and most
assessment methods rely on the memory of the respondent to provide salient
|24. Rehabilitation Engineering Research Center (J. Enderle, U. Conn, & J. Winters, Marquette)|
Student Design Competition: Universal Design for Accessible Medical Instrumentation
Project 1: Wheelchair Platform Device: Persons with disabilities need access to all forms of modern health care, including dental procedures, health care check ups, and diagnostic procedures such as mammography. Unfortunately, barriers are common for persons with disabilities because of patient positioning, comfort and ease of use. A platform device is desired that enables wheelchair users access to health care procedures. The device should have two-degrees of freedom (rotation of 360 degrees, and vertical translation from 3”-9” above the floor).
It should be accessible, which includes addressing the following specifications:
the wheelchair client should be able to wheel onto the device,
going up a small ramp,
Project 2: Weight Scale for Wheelchair Users: For persons at risk for conditions such as Chronic Obstructive Pulmonary Disease (COPD) where changes in body weight carry clinical significance, it is recommended that the person’s weight be monitored at least once per day. Persons with disabilities using a wheelchair often have difficulty weighing themselves using common scales because of the wheelchair and positioning issues, and thus lack access to an important aspect of health care. Others cannot weigh themselves regularly in a home setting because of difficulties in standing for an appropriate length of time. In such cases weight measurement could be made while they sit in a chair or rest on a bed. A weight scale for home use by wheelchair users is desired that is easy to use without assistance, low cost and accurate. The weight scale device should not require the person with disability to leave their wheelchair, and should provide a calibrated weight measure that is easy to see (and/or hear) and preferably recorded digitally so that it can be easily compared to previous measurements. Ideally, there would be feedback to the subject (who may have visual or hearing impairment) when a stable measurement has been obtained. It should be easy to transport and set up within a home, with a caregiver able to move it to another location. Ideally, it should be accessible to the largest number of possible users, and thus also be flexible
|25. Franz Baudenbacher [F.Baudenbacher@Vanderbilt.edu ] Physics & BME|
|26. Mike McDonald, PhD, Department of Pharmacology, 936-1082 firstname.lastname@example.org|
|27. IEEE Computer Society—CSIDC - details below...|
Student Design Teams Sought for
|28. Contact info: John Wikswo: email@example.com Mark Bray: firstname.lastname@example.org Dale Evertson: email@example.com|
|29. Bradford Wood, MD, Sr Clinical Investigator, National Institutes of Health , Diagnostic Radiology Department, 301-496-7739|
|30. Jerry Collins, x23003|
Device and Method to Monitor DNA Hybridization on Microarrays using
This project will involve working with Dr. Tom Whitaker of Atom Sciences, Inc. in Oak Ridge, TN on an NIH-funded project to develop a new method for monitoring hybridization on a DNA Microarray. The project involves device design, modeling of the expected signal, multiplexed measurements of capacitance from a large number of probe sites, and optimization of the kinetics and signal intensity. The initial application of the technology is genetic identification of pathogens and antimicrobial resistance genes in pathogens. A lengthier description of the project is available. Contact Jerry Collins if interested
|31. Alan Bradshaw, Research Assistant Professor, Departments of Surgery and Physics, Vanderbilt University 322-0705 www.vanderbilt.edu/biomag|
|Vector Analyzer for Gastrointestinal Magnetic Field Signals: The student will design a Vector Analyzer to utilize three orthogonal magnetic field components recorded from a Superconducting QUantum Interference Device (SQUID) magnetometer. The Vector Analyzer will provide for optimal detection of the magnetogastrogram (MGG) or magnetoenterogram (MENG) of healthy and diseased tissue. The initial design will be software-based, but the ultimate design could be a microprocessor-based instrument.|
|32. Gary B. Byram, Ph.D, Ben Close, MedTG, LLC|
|33. Dr. Patrick Leu firstname.lastname@example.org x35602 (King & Roselli will co-advise)|
|Develop a software technique to analyze female bladder function data for compliance measurement with the goal of making the process less stressful and painful. (Data has been archived, can be analyzed & compared to physician analysis) A 1-2 person project, good computer skills needed.|
|34. Dr Todd Giorgio|
1 person, prefer BME with computational interests also with expertise in
The aim of this project is optimal design of a magnetic nanocrystal for gene/drug delivery. The most significant portion of the work is prediction of nanocrystal motion in tissue using computational fluid dynamics software (CDFRD). The software is available in our lab and allows creation of a porous media model of tissue, incorporation of magnetic nanocrystals with selectable properties and overlay of a magnetic field. The deliverables will include characterization of nanocrystal dispersion in porous media tissue as a function of tissue, nanocrystal and magnetic field parameters. A portion of the work includes experimental measures in our lab of magnetic field strength as a function of position. This is a multidisciplinary project in collaboration with Dr. Dennis Hallahan (Chair, VU Radiation Oncology) and Professor Mike Miga (BME).
|34 sponsors, 58+ projects, as of 10/29/2003|